This paper presents a computer model of the three-cascade microfluidic generator with a planar design and a characteristic dimension of 100 micrometers. Computer simulation of the working process in the three-cascade microfluidic generator with a planar design and a characteristic dimension of 100 micrometers was performed to determine its nominal and limiting functional characteristics for microfluidic signals. The dependence of the velocity in the supply channel on the differential pressure has been established, and the beginning of the pulse process of the working substance has been identified. Velocity and pressure profiles of the working substance within the structure have been obtained. The results can be applied in the design of highly accurate measuring and control systems for aviation and space technology operating in environments with high intensity electromagnetic fields, high levels of radiation and temperatures.