The concept of a Smart City is to use the existing resources in an optimal way to provide the greatest convenience to its residents. This requires close integration of all components, for example, street video surveillance, public services, intelligent transport systems and others, on the scale of a megalopolis. Every year, the world’s megacities are becoming more comfortable for residents due to the introduction of newest technologies. First, such technologies include intelligent control systems in the transportation field. The main goals of Smart Transportation are the efficient and coordinated movement of people, monitoring the location of objects, fast and reliable interaction of vehicles with each other, as well as guaranteeing road safety. This paper represents examples of artificial intelligence technologies and optimization methods applications to create such smart systems.