72663

Автор(ы): 

Автор(ов): 

8

Параметры публикации

Тип публикации: 

Статья в журнале/сборнике

Название: 

The disease centered multimorbidity model at the example of type 2 diabetes mellitus

ISBN/ISSN: 

1078-6236

DOI: 

10.25728/assa.2023.23.01.1376

Наименование источника: 

  • Advances in Systems Science and Applications

Обозначение и номер тома: 

Vol 23 No1

Город: 

  • Pennsylvania, U.S.A.

Издательство: 

  • International Institute for General Systems Studies

Год издания: 

2023

Страницы: 

22-34
Аннотация
Multimorbidity is a condition when few diseases (multimorbidity pattern) are diagnosed in same patient. According to the disease centered model the pattern is formed around one “marker” disease at the expense of other diseases which have non-random relationships with the “marker” disease and between each other. The totality and probabilistic connections between pairs of diseases determine the specifics of the pattern and indicate the possibilities for managing individual and population health as a result of interactions of all components of the the pattern. Algorithms have been developed assessing the degree of non-random connections between pairs of diseases in the pattern and establishing a hierarchical relationship between both “marker” and other diseases as well as between pairs of non-marker diseases. The calculation of non-random statistical relationships between pairs of diseases included in the T2DM (Type 2 Diabetes Mellitus) multimorbidity pattern proved the consistency of the data obtained with the current clinical description of T2DM pathogenesis and complications.

Библиографическая ссылка: 

Мешков Д.О., Лобанов А.В., Данилова Л.И., Черкасов С.Н., Широкий А.А., Федяева А.В., Мороз И.Н., Макеева Е.Д. The disease centered multimorbidity model at the example of type 2 diabetes mellitus // Advances in Systems Science and Applications. 2023. Vol 23 No1 . С. 22-34.