All The technosphere pollution with various substances has been analyzed considering their impact on human health, depending on the hazard degree. The most frequently occurring in nature hazardous substances have been classified by the degree and class of hazard. The impact of exhaust gases emitted by the recently growing motor vehicle fleet on human health is shown. A new ultrahigh-frequency technique is proposed to monitor the concentration of exhaust gases emitted by vehicles into the atmosphere. Measures are specified that allow reducing the environmental footprint by pursuing a sound environmental policy and introducing innovative technologies.