The process of university digitalization at the present stage includes an information educational environment, electronic office management, financial reporting, various information systems and communication tools. The optimization of university digitalization processes involves the use of the single digital platform for all information processes and university's departments, which provides direct document exchange between the systems. The linking element of digital space formation is, in our opinion, electronic document management. The purpose of the study is to analyze the practice of introducing information systems and technologies into the work of universities, identifying legal and organizational problems arising in this regard, determining the optimal conditions for the introduction of electronic document management. The study analyses the experience of implementation of different electronic document interchange systems (EDMS) as well as the comparison of approaches devoted to electronic document management implementation in other universities. Therefore, EDMS has been chosen. The modeling of the system for the main divisions of the university was carried out using the example of several groups of documents. Experimental approbation of electronic document management in university is implemented. The result of the study is the reasoning of need to develop mutually integrated systems, which model the work of university divisions, branches. The study found that important problems of optimizing the implementation of digitalization practices in universities lie in the legal framework. The argument was made for the internal regulation developing, which, if possible, exclude the duplication of paper and electronic document interchange and parallel maintenance of several information systems.