The contemporary Russian economy needs to update its production base, without which it is impossible to produce high-quality innovative products, achieve high productivity, and gain competitive advantages in global markets. However, most of the country’s manufacturing enterprises today operate on an industrial basis, and it is technical re-equipment, modernization, and the reconstruction of fixed assets that allow companies to use their resources in full using modern technologies, reducing costs while increasing profits. This chapter uses regression analysis to assess the multiplier effects in order to study the influence of external factors, such as investments in the technological transformations of Russian GDP from 2005 to 2018. The most appropriate models with significant parameters and which indicators have the greatest positive effect on economic growth are identified. The results obtained prove the effectiveness of investments in reconstruction and modernization, contributing to increases in gross output and, as a result, strengthening the national economy.