This book reflects the results of research and operational experiences of the Federal State Budgetary Entity “National research center “Institute named after N.E. Zhukovsky” in management of scientific and technological development. This book outlines structure and main processes of this management system as well as main elements of its working tools. Besides general methodological developments of the Center the book briefly represents also particular results of their application for Russian aircraft industry scientific-technological development management.For instance, the highlights of long-term forecast for aircraft science and technological development created by the Center on its own methodology are described. The particular attention is paid to new organizational solutions in the sphere of research and development, those give our country the chance for parity with global competitors in spite of smaller scopes and current backlog in many scientific and technical fields. These ones are cross-sectoral technology transfer and cross-sectoral integration of research and development result. Meanwhile Center’s research and development findings frequently go beyond sectoral applied science. They result in recommendations on improving legal and regulatory support for research and development, structure of scientific and manufacturing organizations. These suggestions are also outlined in this book.