We study nonlocal symmetries of Pleba ́ ski’s second heavenly equation in an infinite-dimensional covering n associated to a Lax pair with a non-removable spectral parameter. We show that all local symmetries of the equation admit lifts to full-fledged nonlocal symmetries in the infinite-dimensional covering. Also, we find two new infinite hierarchies of commuting nonlocal symmetries in this covering and describe the structure of the Lie algebra of the obtained nonlocal symmetries.