Approach to the system’s dynamic modeling and decision-making support development for specialist doctors based on intelligent mathematical models is proposed. Based on intelligence analysis of the content of a global database, the system will dynamically generate the inductive knowledge for different aspects of diagnosis and treatment of cancer. The system in essence will model the decision-making process to guide “a human operator”, which in this case is a doctor who consciously or sub-consciously analyses the situation and makes decisions based on his or her professional knowledge and experience. However, even the most skilled doctor is unable to process the information volume of such proportions and do the multiple factor analysis as deep as his or her assistant - an intelligent computerized system, which is able to instantly focus on the specific developing situation while considering all prior history, and produce a model and a prognosis.