Growing attention to renewable energy in Russia is largely determined by the fact that some of these technologies allow the
processing of anthropogenic waste and by that reduce environmental damage. Heterogeneous economic, geographical and
climatic conditions for the Russian Federation regions development set the scientific task of studying regional practices,
taking into account the existing programs for the renewable energy production development. The objectives of this study
were exploring innovative approaches already used in leading countries of biofuel production organizing as one of the way to
ensure sustainable development, as well as an analysis of existing experience and prerequisites for using such approaches
in certain regions of the Russian`s Central Federal District. As an example, considered some existing indicators and
programs for the fuel and energy sectors development, as well as the results of the individual enterprises in the Belgorod,
Voronezh, Yaroslavl and Kostroma regions long-term activities, which use innovative approaches to the production of
biofuels. Taking into account various regulatory documents recommendations, including instructions of national standards
for innovation management, a number of factors for the effective implementation of innovations in the biofuel production are
highlighted. Particular attention is paid to the biofuel production importance for the solid industrial, agricultural and household
waste, containing organic compounds, processing as a promising way to protect the environment from anthropogenic
pollution, which may be the key to the existing environmental conditions maintaining.