In this paper, a problem of robust anisotropy-based control with regional pole assignment for descriptor systems with norm-bounded parametric uncertainties is concerned. The goal is to find a state-feedback control law, which guarantees desirable disturbance attenuation level from stochastic input with unknown covariance to controllable output of the closed-loop system, and ensures, that all finite eigenvalues of the closed-loop system belong to the given region inside the unit disk for all uncertainties from the given set.