The paper deals with algorithmic issues of the process of separating periods in the pulsed signal of the radial artery. The periodization algorithm is a set of various procedures for processing an impulse signal that can confidently allocate periods in a signal. It precedes the rest of the analysis stages. The procedures used in the algorithm are described. The expediency of their application is discussed. A block diagram of the developed algorithm for pulsed signal periodization is given. The verification of the developed algorithm was carried out on a representative sample. Several variants of the composite algorithm were implemented. As a result, an algorithm was chosen that combined the statistical algorithm and the corrective procedure — a configurable amplitude sieve. The analysis of the results of the developed algorithm has confirmed the acceptable efficiency of the periodization process for very diverse pulse signals.